In 2018, we celebrate our company's 25th anniversary !
Chiralizer™ Services, L.L.C. was
founded by an analytical scientist, William
Letter, in 1993 to provide innovative solutions to the problems of analytical
chemists in the pharmaceutical research industry. Chiralizer™ Services is a
Department of Defense (CCR) listed contractor and currently offers the following products
and services :
- A unique line of proprietary HPLC, UHPLC and LC-MS
- Expert Chiral HPLC / SFC Method Development Advice
- analytical % e.e. determination
- racemic chiral HPLC & SFC method development
- Agilent Technologies / Hewlett-Packard brand
analytical HPLC and LC-MS:
- instrument installation
- instrument performance verification and
qualification (IQ, OQ, PV)
- instrument operation, repair, maintenance and
- Advanced ChemStation operation training classes
- Expert training in the use of the HP 1090, 1050,
1100, 1200, 1260 and 1290-Series HPLCs
- A number of areas of consulting, including :
- General HPLC, UHPLC and LC-MS consulting, including
the set up of new labs, the improvement of existing operations and assistance with complex
separation, method development or instrumentation problems - regardless of equipment
- Diverse customized training classes for individuals
or groups in a number of diverse analytical areas, including chiral method development,
automated method development, development of robotic and high throughput systems, correct
use and optimization of Evaporative Light Scattering Detectors (ELSD), instrument
performance verification, polymer characterization, MW determination, peptide and protein
resolution and data station operation to name a few.
- New and Reconditioned HPLC Instruments and Computers
- HPLC modules and systems, used LC-MS systems,
Spectrophotometers, HP Computers & Workstation Upgrades and HPLC parts for many older
HP brand analytical systems. Please Check our most recent Inventory Listing.
The proprietary products of Chiralizer™
Services have been designed to automate common procedures used in HPLC and LC-MS analyses.
Chiralizer™ Services developed the very popular LC
SPIDERLING ™ Automated Column Selection System - now used by most of the world's
major pharmaceutical, chemical and environmental companies to achieve greater efficiencies
in both sample screening, throughput and in the development of new chromatography methods.
The company's name is derived from the first
application of the LC SPIDERLING™ in the form of an intelligent, automated
method development device for chiral HPLC separations. The original
"Chiralizer™", as it was known, (Short for automated chiral analyzer) was
used to screen racemic samples against a number of proven commercial chiral columns.
Within six months, it enabled the elimination of a backlog of over 600 chiral compounds
waiting for separation methods. To date, over 10,000 unique chiral methods have been
developed using the product for chiral analysis in our laboratory alone.
Because it could automate the method development
and analysis process for most non-chiral (achiral) as well as chiral samples, the
Chiralizer's name was changed to the "LC SPIDERLING™" (it's plumbing
resembles a spiders body and legs), and it became the first in a growing series of
proprietary automation & control devices offered to chemist's.
Chiralizer™ Services can help make your
laboratory more efficient and productive. Many of Our Clients have already discovered
what we can do for them. Shouldn't you ?
© Copyright 1993 to 2013, Chiralizer™
Services, L.L.C. All Rights Reserved. Phone 1-919-241-4858.